KMID : 1138520110140030063
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Journal of Pharmacopuncture 2011 Volume.14 No. 3 p.63 ~ p.69
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Effect of Artemisia capillaries on Gene Expression of Lipid Metabolism in Rat
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Chang Woo-Seok
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Abstract
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Objectives:The purpose of this study is to evaluate the effect of Artemisia capillaries on gene expression of lipid metabolism in rats.
Methods:The author performed several experimental items to analyze the total cholesterol and triglyceride in liver tissue, the gene expressions of CYP7A1 and HMG-CoA reductase.
Results: 1. In Artemisia capillaries group, the levels of total cholesterol in liver tissue were significantly decreased. 2. In Artemisia capillaries group, the ratios of CYP7A1, HMG-CoA reductase were as same as the normal group.
Conclusions:From the above results, Artemisia capillaries can be used to treat hyperlipidemia.
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KEYWORD
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Artemisia capillaries, Hyperlipidemia, Gene expression
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